Can I use the Saffire as an interface with Pro Tools?

The Focusrite Saffire interfaces are designed to work with all ASIO and WDM compliant software on Windows and all CoreAudio compliant software on the Mac.

ProTools 9 now supports the use of 3rd party Core Audio/ASIO compliant interfaces, hence all Focusrite Audio Interfaces can now be used with ProTools.

(Only Digidesign hardware is compatible with earlier versions of Pro Tools.)